Medronic Acid

Medronic Acid

SCHEMBL2817784

O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.[NaH].[NaH].[NaH].[NaH].[NaH]

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.91
MMP2 P08253 1/20 0.91
THRB P10828 1/20 0.91
MAPK1 P28482 1/20 0.91
HSD17B10 Q99714 1/20 0.91
OTC P00480 1/20 0.50
TYMS P04818 1/20 0.44
LMNA P02545 2/20 0.39
BLM P54132 2/20 0.39
MEN1 O00255 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PGK1 P00558 1/20 0.39
PGK2 P07205 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CA2 P00918 1/20 0.36
CYP3A4 P08684 1/20 0.35
NFKB1 P19838 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Medronic Acid SCHEMBL17922880 1.00 KDM4E (0.91) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL4424564 1.00 KDM4E (0.91) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL8958446 1.00 KDM4E (0.91) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL27485770 1.00 KDM4E (0.91) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL5201705 1.00 KDM4E (0.91) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL6365875 1.00 KDM4E (0.91) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL1478332 1.00 KDM4E (0.91) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL10843210 0.96 KDM4E (0.83) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL27363300 0.96 KDM4E (0.83) KDM4EMMP2THRBMAPK1HSD17B10
Medronic Acid SCHEMBL66716 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9030008-B2 Adhesion promoting composition for metal leadframes CITIBANK, N.A. 2015-05-12 US claimed
US-6395698-B1 MIXTURE CONTAINING QUATERNARY AMMONIUM COMPOUND MASON CHEMICAL COMPANY 2002-05-28 US claimed
WO-2014041010-A1 STABILIZATION OF PAINT STRIPPER FORMULATIONS AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2014-03-20 WO disclosed
EP-2683806-A1 STABILIZATION OF SURFACTANTS AGAINST OXIDATIVE ATTACK Akzo Nobel Chemicals International B.V. (NL) 2014-01-15 EP disclosed
WO-2012123313-A1 STABILIZATION OF SURFACTANTS AGAINST OXIDATIVE ATTACK AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2012-09-20 WO disclosed
US-20100249199-A1 Hard Surface Treatment Compositions with Improved Mold or Fungi Remediation Properties RECKITT & COLMAN (OVERSEAS) LIMITED (GB) 2010-09-30 US disclosed
US-7488708-B2 Foaming two-component hard surface cleaning compositions RECKITT BENCKISER INC. (US) 2009-02-10 US disclosed
US-20060276366-A1 FOAMING TWO-COMPONENT HARD SURFACE CLEANING COMPOSITIONS RECKITT BENCKISER INC. (US) 2006-12-07 US disclosed
US-6395698-B1 MIXTURE CONTAINING QUATERNARY AMMONIUM COMPOUND MASON CHEMICAL COMPANY 2002-05-28 US disclosed
US-4871652-A CYANO SUBSTITUTED PHOTOGRAPHIC COUPLER EASTMAN KODAK COMPANY (US) 1989-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249199-A1 Hard Surface Treatment Compositions with Improved Mold or Fungi Remediation Properties DPM1, POLR1C, HAO2 KDM4E 3189/4885MMP2 1705/4885THRB 3852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.