Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7810731 | 0.85 | NCF1 (0.51) | NCF1TLR8KMT2AGUSBELANE | |
| SCHEMBL89579 | 0.84 | NCF1 (0.49) | NCF1KMT2ALMNATP53SMN1; SMN2 | |
| SCHEMBL17310938 | 0.83 | NCF1 (0.47) | NCF1TLR8KMT2AGUSBL3MBTL1 | |
| SCHEMBL4273454 | 0.80 | NCF1 (0.52) | NCF1TLR8KMT2AGUSBELANE | |
| SCHEMBL423902 | 0.80 | CYP1A2 (0.55) | NCF1TLR8GUSBELANETP53 | |
| SCHEMBL28175260 | 0.79 | ADORA1 (0.54) | NCF1TLR8KMT2AGUSBELANE | |
| SCHEMBL7805413 | 0.79 | NCF1 (0.76) | NCF1TLR8GUSBELANE | |
| SCHEMBL31529344 | 0.77 | LMNA (0.69) | TLR8LMNAADORA1ADORA2AKDM4E | |
| SCHEMBL21848421 | 0.76 | NCF1 (0.49) | NCF1TLR8KMT2AGUSBELANE | |
| SCHEMBL4848307 | 0.76 | CYP1A2 (0.58) | KMT2AL3MBTL1KDM4ETP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107674077-A | 8 [base of 3 amino piperidine 1] Xanthine compounds, its preparation method and purposes as pharmaceutical preparation | 勃林格殷格翰制药两合公司 | 2018-02-09 | — | — | CN | disclosed |
| CN-105001222-B | 8 [base of 3 amino piperidine 1] Xanthine compounds, its preparation method and purposes as pharmaceutical preparation | 勃林格殷格翰制药两合公司 | 2017-11-07 | — | — | CN | disclosed |