SCHEMBL28178474

SCHEMBL28178474

Nc1cc2nc3ccccc3cc2c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.60
ESR2 Q92731 7/20 0.60
KMT2A Q03164 3/20 0.59
ALDH1A1 P00352 3/20 0.59
GLA P06280 3/20 0.59
HPGD P15428 3/20 0.59
NPC1 O15118 2/20 0.59
POLB P06746 2/20 0.59
GAA P10253 2/20 0.59
KDM4E B2RXH2 2/20 0.59
RAB9A P51151 2/20 0.59
LMNA P02545 1/20 0.59
PTBP1 P26599 1/20 0.59
RCE1 Q9Y256 1/20 0.59
MAPT P10636 3/20 0.46
MEN1 O00255 1/20 0.46
USP2 O75604 1/20 0.46
CACNA1B Q00975 1/20 0.46
APBA1 Q02410 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3109538 0.85 ALDH1A1 (0.61) ESR1ESR2KMT2AALDH1A1GLA
SCHEMBL28441223 0.81 ESR1 (0.62) ESR1ESR2KMT2AALDH1A1GLA
SCHEMBL28178451 0.81 ESR1 (0.57) ESR1ESR2KMT2AALDH1A1GLA
SCHEMBL28861333 0.78 ESR1 (0.57) ESR1ESR2KMT2AALDH1A1GLA
SCHEMBL27791671 0.76 ESR1 (0.55) ESR1ESR2KMT2AALDH1A1GLA
SCHEMBL196020 0.76 ESR1 (0.59) ESR1ESR2KMT2AALDH1A1GLA
SCHEMBL29664474 0.75 ESR1 (0.58) ESR1ESR2KMT2AALDH1A1GLA
SCHEMBL17141873 0.75 ALDH1A1 (0.61) ESR1ESR2KMT2AALDH1A1GLA
SCHEMBL27956650 0.75 ESR1 (1.00) ESR1ESR2KMT2AALDH1A1GLA
SCHEMBL11766044 0.75 ALDH1A1 (0.61) ESR1ESR2KMT2AALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107337643-A A kind of acridine compound and its organic luminescent device 长春海谱润斯科技有限公司 2017-11-10 CN disclosed
CN-107162974-A A kind of acridine compounds and its organic luminescent device 长春海谱润斯科技有限公司 2017-09-15 CN disclosed