SCHEMBL3109538

SCHEMBL3109538

Nc1ccc2nc3ccccc3cc2c1-c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
GLA P06280 4/20 0.61
HPGD P15428 4/20 0.61
KMT2A Q03164 4/20 0.61
GAA P10253 3/20 0.61
KDM4E B2RXH2 3/20 0.61
POLB P06746 3/20 0.61
RAB9A P51151 3/20 0.61
NPC1 O15118 2/20 0.61
LMNA P02545 2/20 0.61
PTBP1 P26599 1/20 0.61
RCE1 Q9Y256 1/20 0.61
ESR1 P03372 8/20 0.57
ESR2 Q92731 7/20 0.57
MAPT P10636 4/20 0.47
ACHE P22303 3/20 0.47
BACE1 P56817 1/20 0.45
HTR3A P46098 1/20 0.44
IDO1 P14902 1/20 0.42
CASP1 P29466 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28178474 0.85 ESR1 (0.60) ALDH1A1GLAHPGDKMT2AGAA
SCHEMBL28861333 0.83 ESR1 (0.57) ALDH1A1GLAHPGDKMT2AGAA
SCHEMBL196020 0.81 ESR1 (0.59) ALDH1A1GLAHPGDKMT2AGAA
SCHEMBL367365 0.80 ALDH1A1 (0.67) ALDH1A1GLAHPGDKMT2AGAA
Biphenyl SCHEMBL28499425 0.79 ESR1 (0.57) ALDH1A1GLAHPGDKMT2AGAA
SCHEMBL27869747 0.79 ESR1 (0.57) ALDH1A1GLAHPGDKMT2AGAA
SCHEMBL28265821 0.79 ESR1 (0.57) ALDH1A1GLAHPGDKMT2AGAA
SCHEMBL28178451 0.79 ESR1 (0.57) ALDH1A1GLAHPGDKMT2AGAA
Hydrochloric Acid SCHEMBL7768198 0.79 KMT2A (0.65) ALDH1A1GLAHPGDKMT2AGAA
Hydrochloric Acid SCHEMBL28694123 0.79 KMT2A (0.65) ALDH1A1GLAHPGDKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10808275-B2 Use of at least one chromogenic and/or fluorogenic phosphatase substrate for the detection and/or enumeration of enterobacteria in a sample bioMérieux (FR) 2020-10-20 US disclosed
CN-104508140-B The method that detection generates the bacterium of OXA-048 carbapenem enzyme 生物梅里埃公司 2019-03-01 CN disclosed
CN-108048522-A The detection of bacterium with the resistance to Carbapenems 生物梅里埃公司 2018-05-18 CN disclosed
EP-2689026-B1 DETECTION OF BACTERIA HAVING A RESISTANCE TO CARBAPENEMS BIOMERIEUX SA (FR) 2017-03-08 EP disclosed
US-9562899-B2 Method of detecting OXA-048 carbapenemase producing bacteria bioMérieux (FR) 2017-02-07 US disclosed
US-9347888-B2 Detection of bacteria exhibiting a resistance to carbapenems BIOMERIEUX (FR) 2016-05-24 US disclosed
US-20160046976-A1 USE OF AT LEAST ONE CHROMOGENIC AND/OR FLUOROGENIC PHOSPHATASE SUBSTRATE FOR THE DETECTION AND/OR ENUMERATION OF ENTEROBACTERIA IN A SAMPLE BIOMERIEUX (FR) 2016-02-18 US disclosed
EP-2981619-A1 USE OF AT LEAST ONE CHROMOGENIC AND/OR FLUOROGENIC PHOSPHATASE SUBSTRATE FOR THE DETECTION AND/OR ENUMERATION OF ENTEROBACTERIA IN A SAMPLE Biomérieux (FR) 2016-02-10 EP disclosed
US-20150160211-A1 METHOD OF DETECTING OXA-048 CARBAPENEMASE PRODUCING BACTERIA BIOMERIEUX (FR) 2015-06-11 US disclosed
CN-104508140-A Method of detecting OXA-048 carbapenemase producing bacteria BIO MERIEUX INC 2015-04-08 CN disclosed
CN-101631875-A Be used to detect and/or differentiate the medium of bacterium BIOMERIEUX SA 2010-01-20 CN disclosed
CN-101631874-A Be used to detect and/or differentiate the medium of bacterium BIOMERIEUX SA 2010-01-20 CN disclosed
EP-2111461-A2 BACTERIA DETECTION AND/OR IDENTIFICATION MEDIUM BIOMERIEUX (FR) 2009-10-28 EP disclosed
EP-2111462-A2 MEDIUM FOR DETECTING AND/OR IDENTIFYING BACTERIA BIOMERIEUX (FR) 2009-10-28 EP disclosed
EP-2111460-A2 MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA BIOMERIEUX (FR) 2009-10-28 EP disclosed
WO-2008104681-A2 BACTERIA DETECTION AND/OR IDENTIFICATION MEDIUM bioMérieux (FR) 2008-09-04 WO disclosed
WO-2008104679-A2 MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA bioMérieux (FR) 2008-09-04 WO disclosed
WO-2008104680-A2 MEDIUM FOR DETECTING AND/OR IDENTIFYING BACTERIA bioMérieux (FR) 2008-09-04 WO disclosed
EP-1587793-A1 ENZYME SUBSTRATES, CULTURE MEDIA CONTAINING SAME AND USE THEREOF IN ORDER TO DETECT AMINOPEPTIDASE ACTIVITY AND/OR DIFFERENTIATE GRAM-POSITIVE BACTERIA FROM GRAM-NEGATIVE BACTERIA BIOMERIEUX (FR) 2005-10-26 EP disclosed
WO-2004069804-A1 ENZYME SUBSTRATES, CULTURE MEDIA CONTAINING SAME AND USE THEREOF IN ORDER TO DETECT AMINOPEPTIDASE ACTIVITY AND/OR DIFFERENTIATE GRAM-POSITIVE BACTERIA FROM GRAM-NEGATIVE BACTERIA BIOMERIEUX (FR) 2004-08-19 WO disclosed