SCHEMBL28178809

SCHEMBL28178809

CCC(C)N(C(=O)SCc1ccccc1)C(C)CC.CCOC(N)=S

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
POLB P06746 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
IDO1 P14902 6/20 0.39
METAP2 P50579 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
LMNA P02545 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4888977 0.86 IDO1 (0.41) ALDH1A1POLBCYP1A2CYP2C9IDO1
SCHEMBL65715 0.86 IDO1 (0.41) ALDH1A1POLBCYP1A2CYP2C9IDO1
SCHEMBL11795582 0.75 CA12 (0.46) ALDH1A1IDO1HDAC3HDAC4HDAC1
SCHEMBL27841776 0.74 ALDH1A1 (0.33) ALDH1A1IDO1L3MBTL1SMN1; SMN2NPC1
SCHEMBL11859462 0.73 KMT2A (0.45) IDO1L3MBTL1NOS3NOS1NOS2
SCHEMBL11799295 0.72 IDO1 (0.44) ALDH1A1POLBIDO1LMNARAB9A
SCHEMBL11792567 0.72 TDP1 (0.44) ALDH1A1CYP1A2IDO1LMNAL3MBTL1
Diallate SCHEMBL10696405 0.71 TDP1 (0.34) IDO1HDAC3HDAC4HDAC1HDAC7
Diallate SCHEMBL10696403 0.71 TDP1 (0.34) IDO1HDAC3HDAC4HDAC1HDAC7
SCHEMBL10836968 0.71 IDO1 (0.48) ALDH1A1IDO1L3MBTL1TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107207546-A Ligand component, correlated response product, reaction product, the hydrosilylation catalysts comprising the ligand component and the hydrosilylation curable compositions of activation, and for preparing their correlation technique 美国道康宁公司 2017-09-26 CN disclosed