SCHEMBL28181

SCHEMBL28181

O=C(/C=C\c1ccccc1)/C=C/c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 1.00
CYP2C9 P11712 3/20 1.00
F3 P13726 3/20 1.00
CYP1A2 P05177 3/20 1.00
PLIN1 O60240 2/20 1.00
LMNA P02545 2/20 1.00
RECQL P46063 2/20 1.00
PLIN5 Q00G26 2/20 1.00
ABHD5 Q8WTS1 2/20 1.00
CYP2D6 P10635 2/20 1.00
ALDH1A1 P00352 2/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
HDAC3 O15379 2/20 0.73
HDAC4 P56524 2/20 0.73
HDAC1 Q13547 2/20 0.73
HDAC2 Q92769 2/20 0.73
HDAC8 Q9BY41 2/20 0.73
HDAC6 Q9UBN7 2/20 0.73
TNKS O95271 1/20 0.73
HCAR2 Q8TDS4 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20856054 1.00 MAPT (1.00) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL28435740 1.00 MAPT (1.00) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL20518814 1.00 MAPT (1.00) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL478244 1.00 MAPT (1.00) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL22146 1.00 MAPT (1.00) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL20846 1.00 MAPT (1.00) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL5347650 1.00 MAPT (1.00) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL187662 0.97 MAPT (0.95) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL21879664 0.97 MAPT (0.95) MAPTCYP2C9F3CYP1A2PLIN1
SCHEMBL7265797 0.97 MAPT (0.95) MAPTCYP2C9F3CYP1A2PLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 25922 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4613332-A2 COT MODULATORS AND METHODS OF USE THEREOF Gilead Sciences, Inc. (US) 2025-09-10 EP claimed
EP-4594306-A1 SYNTHESIS METHODS AND INTERMEDIATES FOR THE PRODUCTION OF REMIBRUTINIB Novartis AG (CH) 2025-08-06 EP claimed
WO-2025098181-A1 TRIDENTATE COORDINATED AMINOQUINOLINE SINGLE-SITE COMPLEX, PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油天然气股份有限公司 2025-05-15 WO claimed
CN-119998265-A Synthetic methods and intermediates for the production of rebaudinib 诺华股份有限公司 2025-05-13 CN claimed
EP-4543841-A2 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES The University of North Carolina at Chapel Hill (US) 2025-04-30 EP claimed
US-20250092179-A1 PHOTOSTABLE COMPOSITIONS COMPRISING PARA-ALKOXYL PHENYL SUBSTITUTED PROPENOIC ACID (APP) COPOLYMER DERIVATIVES HallStar Beauty and Personal Care Innovations Company 2025-03-20 US claimed
CN-119615315-A Selective roughening method for different parts of electroplated part 崇辉半导体(江门)有限公司 2025-03-14 CN claimed
CN-119552107-A Heteroaromatic amide CYP1B1 enzyme inhibitor, and preparation method and application thereof 沈阳药科大学 2025-03-04 CN claimed
CN-119528952-A Method for preparing cis-2-boron-alpha-carboglucosides in stereoselective manner 武汉大学 2025-02-28 CN claimed
CN-116444906-B Dibenzylidene acetone modified hydrophobic butyl rubber damping composite material and preparation method thereof 常州浩达科技股份有限公司 2025-02-21 CN claimed
EP-0070200-B1 PROCESS FOR THE PREPARATION OF DIESTERS OF SATURATED CARBOXYLIC ACIDS Montedison S.p.A. (IT) 1984-10-10 EP claimed
US-4429147-A Process for the preparation of diesters of saturated carboxylic acids MONTEDISON S.P.A. (IT) 1984-01-31 US claimed
US-4414417-A Process for the catalytic reduction of unsaturated ketones MONTEDISON, S.P.A. (IT) 1983-11-08 US claimed
EP-0070200-A1 Process for the preparation of diesters of saturated carboxylic acids Montedison S.p.A. (IT) 1983-01-19 EP claimed
US-4321319-A Photosensitive compositions containing polyamides acid with photosensitive groups HITACHI, LTD. (JP) 1982-03-23 US claimed
US-4258121-A SULFONYLOXY N-SUBSTITUTED IMIDES AS PHOTOINITIATORS FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US claimed
US-4160107-A PROCESS FOR THE PREPARATION OF ESTERS OF OXALIC ACID MONTEDISON S.P.A. (IT) 1979-07-03 US claimed
US-4028384-A HYDROSILYLATION WITH A HYDROGEN SILANE, PLATINUM COMPLEX CATALYST DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-06-07 US claimed
US-3998833-A CORROSION INHIBITORS, MICROBIOCIDES PETROLITE CORPORATION (US) 1976-12-21 US claimed
US-3993807-A Activation of substrates for electroless metallization with zero valent palladium complex BASF AKTIENGESELLSCHAFT (DT) 1976-11-23 US claimed