Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 3/20 | 1.00 |
| ▸ | F3 | P13726 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 1.00 |
| ▸ | PLIN1 | O60240 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 1.00 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.73 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.73 |
| ▸ | TNKS | O95271 | 1/20 | 0.73 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20856054 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL28435740 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL20518814 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL478244 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL22146 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL20846 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL28181 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL187662 | 0.97 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL21879664 | 0.97 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL7265797 | 0.97 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925613-A | Preparation method of near-infrared two-region squaraine type fluorescence imaging reagent, nano-composite and application thereof | 南昌大学 | 2023-04-07 | — | — | CN | claimed |
| CN-115093313-A | Cyclopentadiene derived from multi-methyl substituted spiroindane, rhodium complex thereof, preparation method, intermediate and application | 中国科学院上海有机化学研究所 | 2022-09-23 | — | — | CN | claimed |
| WO-2007089193-A1 | A PROCESS FOR PREPARING 2-HYDROXY-3- [5- (MORPHOLIN-4-YLMETHYL)PYRIDIN-2-YL] LH-INDOLE-5-CARBONITRILE AS A FREE BASE OR SALTS THEREOF | ASTRAZENECA AB (SE) | 2007-08-09 | — | — | WO | claimed |
| CN-114349773-B | Carborane orange luminescent material, preparation method thereof and luminescent film | 盐城工学院 | 2023-08-18 | — | — | CN | disclosed |
| CN-109804043-B | Organic light emitting element having long life, low voltage and high efficiency characteristics | SFC株式会社 | 2023-05-30 | — | — | CN | disclosed |
| CN-115925613-A | Preparation method of near-infrared two-region squaraine type fluorescence imaging reagent, nano-composite and application thereof | 南昌大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115093313-A | Cyclopentadiene derived from multi-methyl substituted spiroindane, rhodium complex thereof, preparation method, intermediate and application | 中国科学院上海有机化学研究所 | 2022-09-23 | — | — | CN | disclosed |
| CN-114478499-A | Spirofluorene anthracene compound and application thereof | 阜阳欣奕华材料科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-109804009-B | Organic light emitting diode | 株式会社LG化学 | 2020-10-16 | — | — | CN | disclosed |
| CN-110832657-A | Organic light emitting element with high efficiency | SFC株式会社 | 2020-02-21 | — | — | CN | disclosed |
| WO-2019063748-A1 | ROR-GAMMA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-04-04 | — | — | WO | disclosed |
| EP-1105389-A4 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2001-10-17 | — | — | EP | disclosed |
| EP-1105389-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2001023346-A2 | PROCESS FOR PHENYLACETIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2001-04-05 | — | — | WO | disclosed |
| EP-1040111-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-10-04 | — | — | EP | disclosed |
| US-6090944-A | Alkanoic acid derivatives as αv integrin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |
| WO-2000009503-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| US-6017926-A | Integrin receptor antagonists | MERCK & CO., INC. (US) | 2000-01-25 | — | — | US | disclosed |
| WO-1999031099-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| US-4347232-A | Preparation of hydrogen peroxide from its elements | FMC CORPORATION (US) | 1982-08-31 | — | — | US | disclosed |