Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 3/20 | 1.00 |
| ▸ | F3 | P13726 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 1.00 |
| ▸ | PLIN1 | O60240 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 1.00 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.73 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.73 |
| ▸ | TNKS | O95271 | 1/20 | 0.73 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20856054 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL28435740 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL20518814 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL22146 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL20846 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL28181 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL5347650 | 1.00 | MAPT (1.00) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL187662 | 0.97 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL21879664 | 0.97 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 | |
| SCHEMBL7265797 | 0.97 | MAPT (0.95) | MAPTCYP2C9F3CYP1A2PLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100579965-C | Process for preparing N-heteroaryl-N-arylamines by reacting N-aryl carbamates with haloheteroaryls and analogous processes | VERTEX PHARMA CO LTD | 2010-01-13 | — | — | CN | claimed |
| CN-118488944-A | Nitrogen-containing heterocyclic compound having Nrf2 activation | 中外制药株式会社 | 2024-08-13 | — | — | CN | disclosed |
| CN-118317774-A | Pharmaceutical compositions comprising quinazoline compounds | 安斯泰来制药株式会社 | 2024-07-09 | — | — | CN | disclosed |
| CN-117957225-A | Compounds for targeting degradation of IRAK4 proteins | 渤健马萨诸塞州股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-111491914-B | Novel cationic quaternary ammonium compound, composition comprising the same and process for producing the same | 罗地亚经营管理公司 | 2024-04-26 | — | — | CN | disclosed |
| EP-3755760-B1 | PROCESSES FOR THE MANUFACTURE OF SECONDARY FATTY ALCOHOLS, INTERNAL OLEFINS AND INTERNAL OLEFIN SULFONATES | SPECIALTY OPERATIONS FRANCE (FR) | 2024-02-21 | — | — | EP | disclosed |
| CN-112384491-B | Method for producing alpha-fluoroacrylic acid compound | 大金工业株式会社 | 2024-02-13 | — | — | CN | disclosed |
| CN-117483004-A | Palladium-containing composition and method for producing hydrogen peroxide | 三菱瓦斯化学株式会社 | 2024-02-02 | — | — | CN | disclosed |
| CN-117285547-A | Macrocyclic compounds as modulators of CFTR, pharmaceutical compositions thereof, their use and methods of preparation | 弗特克斯药品有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-111801398-B | Process for the manufacture of secondary aliphatic alcohols, internal olefins and internal olefin sulfonates | 罗地亚经营管理公司 | 2023-11-07 | — | — | CN | disclosed |
| WO-2003072561-A1 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES USEFUL IN THE TREATMENT OF HYPER-PROLIFERATIVE DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-09-04 | — | — | WO | disclosed |
| WO-2003027074-A1 | PYRAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF HYPER-PROLIFERATIVE DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |
| US-20030055085-A1 | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists | ASTRAZENECA AB (SE) | 2003-03-20 | — | — | US | disclosed |
| WO-2003020714-A1 | POLYESTER POLYCARBONATES MADE FROM SPECIAL DIPHENOLS | BAYER MATERIALSCIENCE AG (DE) | 2003-03-13 | — | — | WO | disclosed |
| WO-2002068417-A3 | HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | SLASSI ABDELMALIK (CA) | 2002-11-14 | — | — | WO | disclosed |
| US-20020169188-A1 | Novel amines as histamine-3 receptor ligands and their therapeutic applications | ABBVIE INC. | 2002-11-14 | — | — | US | disclosed |
| US-20020165405-A1 | Process for preparing organically-substituted polyoxometalates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2002-11-07 | — | — | US | disclosed |
| WO-2002068417-A2 | HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | NPS PHARMACEUTICALS, INC. (US) | 2002-09-06 | — | — | WO | disclosed |
| WO-2001018528-A1 | METHOD OF ANALYZING MULTIPLE SAMPLES SIMULTANEOUSLY BY DETECTING ABSORPTION AND SYSTEMS FOR USE IN SUCH A METHOD | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2001-03-15 | — | — | WO | disclosed |
| WO-1996005178-A1 | SYNTHESIS OF BENZODIAZEPINES | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1996-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165405-A1 | Process for preparing organically-substituted polyoxometalates | TET2, ALKBH3, FTO | MAPT 2662/4885CYP2C9 1110/4885F3 1981/4885 |
| US-20020169188-A1 | Novel amines as histamine-3 receptor ligands and their therapeutic applications | HRH3, HRH4, HRH1 | MAPT 3342/4885CYP2C9 1912/4885F3 1081/4885 |
| US-20030055085-A1 | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists | GRM2, GRIN2A, GRM1 | MAPT 659/4885CYP2C9 4234/4885F3 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.