SCHEMBL28181528

SCHEMBL28181528

C=CC(=O)C(=O)C(=O)C=C

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
ALDH1A1 P00352 4/20 0.44
TSHR P16473 4/20 0.44
FGFR4 P22455 1/20 0.44
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2751659 0.82
SCHEMBL1162186 0.82
SCHEMBL16392696 0.77
Biphenyl SCHEMBL27490389 0.76 AKT1 (0.48) LMNAALDH1A1TSHR
SCHEMBL28991689 0.75 LMNA (0.47) LMNAALDH1A1TSHRFGFR4MAPK1
SCHEMBL5702582 0.72 LMNA (0.44) LMNAALDH1A1TSHRFGFR4MAPK1
SCHEMBL326495 0.72
SCHEMBL4753076 0.72
SCHEMBL1906881 0.72
Acrylic Acid SCHEMBL11592332 0.70 LMNA (0.91) LMNAALDH1A1TSHRFGFR4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117285046-B Preparation method of modified mica nano-sheet and mica@nanocellulose fiber, flexible insulating paper and preparation method 四川大学 2024-01-26 CN claimed
CN-117285046-A Preparation method of modified mica nano-sheet and mica@nanocellulose fiber, flexible insulating paper and preparation method 四川大学 2023-12-26 CN claimed
CN-115028560-A Gem-difluoroallyl compound and preparation method thereof 昆明理工大学 2022-09-09 CN claimed
CN-114436935-A Method for synthesizing optically active beta-aminoketone derivative by asymmetric conjugate addition 河南师范大学 2022-05-06 CN claimed
CN-114249639-A Method for efficiently catalyzing degradation cyclization of polypropylene ketone (ester) with high selectivity 复旦大学 2022-03-29 CN claimed
CN-111646937-B Propenone derivative of N-acetyl ciprofloxacin and preparation method and application thereof 河南大学 2022-01-21 CN claimed
CN-111646938-B Propenone derivative of pefloxacin, and preparation method and application thereof 河南大学 2022-01-21 CN claimed
CN-121487955-A Crystal form containing acrylketone biological inhibitor and preparation method and application thereof 上海翰森生物医药科技有限公司 2026-02-06 CN disclosed
CN-121487955-A Crystal form containing acrylketone biological inhibitor and preparation method and application thereof 上海翰森生物医药科技有限公司 2026-02-06 CN disclosed
CN-115624773-B Devolatilizer and method for removing micromolecular substances in polyether polyol and reducing odor 万华化学集团股份有限公司 2025-04-01 CN disclosed
CN-119371440-A Salt containing acrylketone biological inhibitor, salt crystal form, preparation method and application thereof 上海翰森生物医药科技有限公司 2025-01-28 CN disclosed
CN-119371440-A Salt containing acrylketone biological inhibitor, salt crystal form, preparation method and application thereof 上海翰森生物医药科技有限公司 2025-01-28 CN disclosed
CN-119371440-A Salt containing acrylketone biological inhibitor, salt crystal form, preparation method and application thereof 上海翰森生物医药科技有限公司 2025-01-28 CN disclosed
CN-114031066-A Novel method for solvent-free sol-gel polymerization and production of adjustable carbon structures therefrom 14集团技术公司 2022-02-11 CN disclosed
CN-111646937-B Propenone derivative of N-acetyl ciprofloxacin and preparation method and application thereof 河南大学 2022-01-21 CN disclosed
CN-111646937-B Propenone derivative of N-acetyl ciprofloxacin and preparation method and application thereof 河南大学 2022-01-21 CN disclosed
CN-111646938-B Propenone derivative of pefloxacin, and preparation method and application thereof 河南大学 2022-01-21 CN disclosed
CN-111646938-B Propenone derivative of pefloxacin, and preparation method and application thereof 河南大学 2022-01-21 CN disclosed
CN-107400057-B The N- alkylated reaction of nickel catalysis prepares secondary amine or N '-alkyl hydrazine 山东师范大学 2019-09-24 CN disclosed
CN-107400057-A The N alkylated reactions of nickel catalysis prepare secondary amine or N ' alkyl hydrazines 山东师范大学 2017-11-28 CN disclosed