Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27810329 | 0.98 | AKT1 (0.46) | AKT1TGM2ALDH1A1EGFRTP53 | |
| Biphenyl SCHEMBL1311763 | 0.82 | LMNA (0.56) | AKT1TGM2ALDH1A1EGFRTP53 | |
| Biphenyl SCHEMBL36309 | 0.82 | LMNA (0.56) | AKT1TGM2ALDH1A1EGFRTP53 | |
| Biphenyl SCHEMBL8536203 | 0.80 | AKT1 (0.52) | AKT1TGM2ALDH1A1EGFRTP53 | |
| Biphenyl SCHEMBL27428185 | 0.78 | ALDH1A1 (0.55) | AKT1TGM2ALDH1A1EGFRTP53 | |
| Biphenyl SCHEMBL7005540 | 0.78 | TSHR (0.55) | AKT1TGM2ALDH1A1EGFRTP53 | |
| Biphenyl SCHEMBL22032284 | 0.78 | LMNA (0.50) | AKT1TGM2ALDH1A1EGFRTP53 | |
| Biphenyl SCHEMBL1539344 | 0.78 | TSHR (0.55) | AKT1TGM2ALDH1A1EGFRTP53 | |
| Biphenyl SCHEMBL28220204 | 0.73 | ALDH1A1 (0.60) | AKT1ALDH1A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL6013236 | 0.73 | AKT1 (0.75) | AKT1ALDH1A1EGFRTP53PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103159695-A | Thiazole compound capable of restraining human immunodeficiency virus (HIV) replication and effective against drug-resistant HIV virus strains and preparation method and purpose thereof | UNIV CAPITAL NORMAL | 2013-06-19 | — | — | CN | disclosed |
| CN-103153945-A | 1-oximino-3-phenyl-propanes | HOFFMANN LA ROCHE | 2013-06-12 | — | — | CN | disclosed |
| CN-102099435-A | Azapyrenes for electronic applications | BASF SE | 2011-06-15 | — | — | CN | disclosed |
| CN-101243081-A | Pyrido[2,3-d]pyrimidine-2,4-diamine compounds as PTP1B inhibitors | HOFFMANN LA ROCHE (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-1174955-C | 3-amino-2-benzyl-1-phenyl-propane derivs. | — | 2004-11-10 | — | — | CN | disclosed |
| CN-1373745-A | 3-amino-2-benzyl-1-phenyl-propane derivs. | GREULENTHAL GMBH (DE) | 2002-10-09 | — | — | CN | disclosed |