Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 10/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28217615 | 0.83 | CYP4F2 (0.41) | AKT1HTTGAAMAPK1SMN1; SMN2 | |
| SCHEMBL5447282 | 0.77 | TSHR (0.41) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL21381488 | 0.75 | THRB (0.37) | TSHRTHRBTDP1MAPK1 | |
| SCHEMBL11225142 | 0.74 | NAAA (0.38) | TSHRHTTCES2GAAMAPK1 | |
| SCHEMBL11225149 | 0.74 | NAAA (0.38) | TSHRHTTCES2GAAMAPK1 | |
| SCHEMBL11229711 | 0.74 | NAAA (0.38) | TSHRHTTCES2GAAMAPK1 | |
| SCHEMBL5443893 | 0.73 | TSHR (0.39) | TSHRTHRBHTTPOLBAPEX1 | |
| Cyclohexane SCHEMBL8106220 | 0.72 | TSHR (0.89) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL2475630 | 0.72 | TSHR (0.96) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL11775454 | 0.71 | TSHR (1.00) | TSHRTHRBHTTPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107272343-A | Chemical amplification type positive photosensitive polymer combination | 东京应化工业株式会社 | 2017-10-20 | — | — | CN | disclosed |