Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 2/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28240913 | 0.79 | KCNE1 (0.42) | KCNE1KCNQ1LMNAABCB1ALDH1A1 | |
| SCHEMBL3409162 | 0.77 | KCNE1 (0.38) | KCNE1KCNQ1LMNAABCB1ALDH1A1 | |
| SCHEMBL28240889 | 0.77 | KCNE1 (0.38) | KCNE1KCNQ1LMNAALDH1A1HTR2B | |
| SCHEMBL17929070 | 0.77 | KCNE1 (0.43) | KCNE1KCNQ1LMNAABCB1ALDH1A1 | |
| SCHEMBL15254619 | 0.77 | KCNE1 (0.43) | KCNE1KCNQ1LMNAABCB1ALDH1A1 | |
| SCHEMBL28241727 | 0.76 | LMNA (0.35) | KCNE1KCNQ1LMNAALDH1A1HTR2B | |
| SCHEMBL24151289 | 0.75 | KCNE1 (0.42) | KCNE1KCNQ1LMNAABCB1ALDH1A1 | |
| SCHEMBL2818050 | 0.75 | KCNE1 (0.49) | KCNE1KCNQ1ABCB1KDM4EMAOA | |
| SCHEMBL28228605 | 0.75 | KCNE1 (0.42) | KCNE1KCNQ1LMNAABCB1ALDH1A1 | |
| SCHEMBL13380562 | 0.73 | IDO1 (0.44) | KCNE1KCNQ1LMNAABCB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473498-A | Pyrazolo [1,5a] pyrimidine derivatives as IRAK4 conditioning agents | 豪夫迈·罗氏有限公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-105209447-B | Bicyclic [2.2.2] sour GPR120 conditioning agents | 百时美施贵宝公司 | 2017-11-21 | — | — | CN | disclosed |