Catechol

Catechol

SCHEMBL28181589

CC(C)(C)Oc1ccc(OC(C)(C)C)cc1.Oc1ccccc1O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.48
CYP3A4 P08684 4/20 0.48
LMNA P02545 4/20 0.48
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 3/20 0.48
HPGD P15428 3/20 0.48
ALOX15 P16050 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
CA2 P00918 2/20 0.48
RAB9A P51151 2/20 0.48
HIF1A Q16665 2/20 0.48
HSD17B10 Q99714 2/20 0.48
NPC1 O15118 1/20 0.48
CA12 O43570 1/20 0.48
GMNN O75496 1/20 0.48
EGFR P00533 1/20 0.48
FYN P06241 1/20 0.48
POLB P06746 1/20 0.48
CA3 P07451 1/20 0.48
MMP9 P14780 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Catechol SCHEMBL27850850 0.94 KDM4E (0.48) MAPTCYP3A4LMNAALDH1A1KDM4E
Pyrogallol SCHEMBL28079732 0.86 ALDH1A1 (0.52) MAPTCYP3A4LMNAALDH1A1KDM4E
Phenol SCHEMBL28106741 0.84 CA12 (0.50) MAPTCYP3A4LMNAALDH1A1KDM4E
SCHEMBL20588893 0.82 TSHR (0.44) MAPTCYP3A4LMNAALDH1A1KDM4E
SCHEMBL26746 0.82 SLC6A2 (0.44) MAPTCYP3A4ALDH1A1KDM4EHPGD
Hydroquinone SCHEMBL28076396 0.80 MEN1 (0.57) MAPTCYP3A4LMNAALDH1A1KDM4E
SCHEMBL57369 0.80 MEN1 (0.57) MAPTCYP3A4LMNAALDH1A1KDM4E
SCHEMBL93074 0.79 CA4 (0.48) MAPTCYP3A4ALDH1A1ALOX15TDP1
SCHEMBL10405698 0.79 CA4 (0.48) MAPTCYP3A4ALDH1A1ALOX15TDP1
SCHEMBL1052285 0.79 ALDH1A1 (0.46) MAPTCYP3A4LMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107532129-A Efficient small volume nucleic acid synthesis 生命技术公司 2018-01-02 CN disclosed