SCHEMBL1052285

SCHEMBL1052285

CC(C)(C)Oc1ccc(O)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
ALOX15 P16050 4/20 0.46
HSD17B10 Q99714 3/20 0.46
HPGD P15428 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
KIF11 P52732 1/20 0.42
NQO2 P16083 1/20 0.41
RELA Q04206 1/20 0.41
TRPA1 O75762 1/20 0.41
LMNA P02545 2/20 0.40
CYP2C9 P11712 2/20 0.40
NR1I2 O75469 1/20 0.40
MIF P14174 1/20 0.40
TYR P14679 1/20 0.40
HTT P42858 1/20 0.40
NFE2L2 Q16236 1/20 0.40
ADRB2 P07550 3/20 0.40
IGF1R P08069 1/20 0.39
APP P05067 1/20 0.39
KDM4E B2RXH2 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339833 0.86 KIF11 (0.42) ALDH1A1ALOX15HSD17B10HPGDKIF11
SCHEMBL7887616 0.83 ESR1 (0.52) ALDH1A1ALOX15HSD17B10HPGDTDP1
SCHEMBL31376356 0.83 TMEM97 (0.40) ALDH1A1ALOX15HSD17B10HPGDTDP1
SCHEMBL10595513 0.81 ALDH1A1 (0.59) ALDH1A1ALOX15HSD17B10TDP1LMNA
SCHEMBL4615608 0.81 ALDH1A1 (0.60) ALDH1A1ALOX15HSD17B10HPGDTDP1
SCHEMBL23159756 0.81 ALDH1A1 (0.48) ALDH1A1ALOX15HSD17B10HPGDTDP1
SCHEMBL22483101 0.79 MTNR1A (0.42) ALDH1A1ALOX15HSD17B10HPGDKIF11
SCHEMBL28924802 0.79 PRKCE (0.41) ALDH1A1TDP1KIF11LMNAHTT
Catechol SCHEMBL28181589 0.79 MAPT (0.48) ALDH1A1ALOX15HSD17B10HPGDTDP1
Catechol SCHEMBL27850850 0.78 KDM4E (0.48) ALDH1A1ALOX15HSD17B10HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3930862-A DYE DEVELOPER TRANSFER PHOTOSENSITIVE MATERIAL WITH SUBSTITUTED CATECHOL AUXILIARY DEVELOPER FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed
EP-2318477-B1 ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES FUJIFILM ELECTRONIC MAT USA INC (US) 2019-06-05 EP disclosed
US-8252704-B2 Additives to prevent degradation of cyclic alkene derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2012-08-28 US disclosed
US-20110259242-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-10-27 US disclosed
US-7985350-B2 Additives to prevent degradation of cyclic alkene derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-07-26 US disclosed
EP-2318477-A1 ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES FujiFilm Electronic Materials USA, Inc. (US) 2011-05-11 EP disclosed
US-20110091651-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-04-21 US disclosed
US-7871536-B2 Additives to prevent degradation of cyclic alkene derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-01-18 US disclosed
WO-2010005937-A1 ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2010-01-14 WO disclosed
US-20090291210-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2009-11-26 US disclosed
CN-100442092-C Optical film and liquid crystal display element NIPPON OIL CORP (JP) 2008-12-10 CN disclosed
CN-100442091-C Optical film and liquid crystal display element NIPPON OIL CORP (JP) 2008-12-10 CN disclosed
CN-1759333-A Optical film and liquid crystal display element NIPPON OIL CORP (JP) 2006-04-12 CN disclosed
CN-1759334-A Optical film and liquid crystal display element NIPPON OIL CORP (JP) 2006-04-12 CN disclosed
US-4212645-A Hair dyeing composition containing an aryldiamine and a substituted catechol LEVER BROTHERS COMPANY (US) 1980-07-15 US disclosed
US-3930862-A DYE DEVELOPER TRANSFER PHOTOSENSITIVE MATERIAL WITH SUBSTITUTED CATECHOL AUXILIARY DEVELOPER FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110259242-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives GPX4, GPX1, NFE2L2 ALDH1A1 69/4885ALOX15 82/4885HSD17B10 264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.