SCHEMBL28181723

SCHEMBL28181723

C=CC(=O)OCOC(=O)c1ccccc1C(=O)OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.51
TSHR P16473 8/20 0.47
LMNA P02545 2/20 0.46
ALDH1A1 P00352 6/20 0.45
HSD17B10 Q99714 4/20 0.45
CFTR P13569 1/20 0.45
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 3/20 0.44
POLB P06746 2/20 0.44
ATM Q13315 1/20 0.44
THRB P10828 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GLA P06280 1/20 0.42
TP53 P04637 1/20 0.41
MAPK1 P28482 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA5A P35218 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29124872 0.92 CYP3A4 (0.59) CYP3A4TSHRLMNAALDH1A1HSD17B10
SCHEMBL7776152 0.88 TSHR (0.60) CYP3A4TSHRLMNAALDH1A1HSD17B10
SCHEMBL31091399 0.88 TSHR (0.66) CYP3A4TSHRLMNAALDH1A1HSD17B10
SCHEMBL28053505 0.88 TSHR (0.66) CYP3A4TSHRLMNAALDH1A1HSD17B10
SCHEMBL29124873 0.86 ALDH1A1 (0.54) CYP3A4TSHRLMNAALDH1A1HSD17B10
SCHEMBL23071588 0.85 TSHR (0.55) CYP3A4TSHRLMNAALDH1A1HSD17B10
SCHEMBL12181905 0.85 TSHR (0.58) CYP3A4TSHRLMNAALDH1A1HSD17B10
SCHEMBL13415051 0.84 CYP3A4 (0.47) CYP3A4TSHRLMNAALDH1A1HSD17B10
SCHEMBL28016565 0.84 TSHR (0.54) CYP3A4TSHRLMNAALDH1A1HSD17B10
SCHEMBL27993932 0.82 ADRB2 (0.51) CYP3A4TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107394090-A Barrier film for rechargeable battery and the lithium rechargeable battery group comprising it 三星SDI株式会社 2017-11-24 CN disclosed