SCHEMBL28181981

SCHEMBL28181981

O=C(O)c1cc(C(=O)Oc2ccccc2)cc(S(=O)(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.62
FYN P06241 1/20 0.62
NSD2 O96028 1/20 0.53
MAPT P10636 8/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
ALOX5 P09917 1/20 0.48
TMPRSS15 P98073 2/20 0.45
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TDP1 Q9NUW8 3/20 0.41
PARP10 Q53GL7 1/20 0.41
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TSHR P16473 1/20 0.41
PRSS1 P07477 1/20 0.41
ACR P10323 1/20 0.41
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27992061 0.95 NSD2 (0.57) LCKFYNNSD2MAPTSMN1; SMN2
SCHEMBL8669360 0.94 NSD2 (0.56) LCKFYNNSD2MAPTSMN1; SMN2
SCHEMBL11579444 0.87 NSD2 (0.67) NSD2MAPTSMN1; SMN2ALOX5TMPRSS15
SCHEMBL28646749 0.85 LCK (0.46) LCKFYNNSD2MAPTSMN1; SMN2
SCHEMBL8898035 0.83 GAA (0.54) NSD2MAPTSMN1; SMN2ALOX5TMPRSS15
SCHEMBL2673547 0.81 GAA (0.53) NSD2MAPTSMN1; SMN2TMPRSS15ALDH1A1
SCHEMBL2035745 0.81 NSD2 (0.74) NSD2MAPTSMN1; SMN2ALOX5TMPRSS15
SCHEMBL8899186 0.80 MAPT (0.67) NSD2MAPTSMN1; SMN2ALOX5TMPRSS15
SCHEMBL8669362 0.79 NSD2 (0.54) NSD2MAPTSMN1; SMN2ALOX5TMPRSS15
SCHEMBL1423194 0.79 LCK (0.48) LCKFYNNSD2MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107287692-A Polymer-coated sulfonated polyester silver nano-grain bicomponent filament yarn and preparation method thereof 施乐公司 2017-10-24 CN disclosed