SCHEMBL8898035

SCHEMBL8898035

O=C(Oc1ccccc1)c1cccc(S(=O)(=O)O)c1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
MAPT P10636 8/20 0.51
TDP1 Q9NUW8 3/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
NSD2 O96028 1/20 0.50
MAPK1 P28482 1/20 0.50
KMT2A Q03164 4/20 0.49
PABPC1 P11940 1/20 0.49
EIF4H Q15056 1/20 0.49
CTDSP1 Q9GZU7 1/20 0.49
ALDH1A1 P00352 3/20 0.48
TSHR P16473 1/20 0.47
MEN1 O00255 2/20 0.47
PARP10 Q53GL7 1/20 0.46
TMPRSS15 P98073 1/20 0.46
ALOX5 P09917 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2673547 0.98 GAA (0.53) GAANPSR1MAPTTDP1SMN1; SMN2
SCHEMBL27992061 0.87 NSD2 (0.57) GAANPSR1MAPTTDP1SMN1; SMN2
SCHEMBL3296959 0.86 MAPT (0.50) GAANPSR1MAPTTDP1SMN1; SMN2
SCHEMBL8669360 0.85 NSD2 (0.56) GAANPSR1MAPTTDP1SMN1; SMN2
SCHEMBL2673549 0.84 MAPT (0.51) GAANPSR1MAPTTDP1SMN1; SMN2
SCHEMBL6570443 0.83 NPSR1 (0.53) GAANPSR1MAPTTDP1SMN1; SMN2
SCHEMBL28181981 0.83 LCK (0.62) GAANPSR1MAPTTDP1SMN1; SMN2
SCHEMBL69684 0.82 NSD2 (0.63) MAPTTDP1NSD2MAPK1KMT2A
SCHEMBL27701837 0.82 KMT2A (0.51) GAANPSR1MAPTTDP1SMN1; SMN2
SCHEMBL2490813 0.81 PARP10 (0.59) MAPTTDP1SMN1; SMN2KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5644017-A SOLVENT RESISTANCE, FLAME RESISTANCE, MOLDING MATERIALS THE DOW CHEMICAL COMPANY (US) 1997-07-01 US disclosed