Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10112072 | 0.68 | — | — | |
| SCHEMBL6633592 | 0.67 | NPSR1 (0.35) | ALDH1A1KMT2ARAB9ANPC1TSHR | |
| SCHEMBL16684426 | 0.65 | NISCH (0.37) | NISCHALDH1A1KMT2ANOTUMGAA | |
| SCHEMBL13523667 | 0.65 | TP53 (0.32) | — | |
| SCHEMBL5601005 | 0.64 | ALDH1A1 (0.36) | CFTRGOPCALDH1A1KMT2ARAB9A | |
| SCHEMBL1068403 | 0.63 | — | — | |
| SCHEMBL7212942 | 0.61 | ALDH1A1 (0.53) | CFTRGOPCALDH1A1KMT2ACHRNB4 | |
| SCHEMBL868869 | 0.61 | CFTR (0.68) | CFTRGOPCALDH1A1KMT2ARAB9A | |
| Biphenyl SCHEMBL27383049 | 0.60 | ALDH1A1 (0.75) | ALDH1A1KMT2ARAB9ANPC1MAPK1 | |
| SCHEMBL28385903 | 0.59 | CYP1A2 (0.38) | CFTRGOPCKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107200705-B | A kind of preparation method of 3- nitro -2- indolone derivatives | 宁波大学 | 2019-09-13 | — | — | CN | disclosed |
| CN-107200705-A | A kind of preparation method of the indolone derivatives of 3 nitro 2 | 宁波大学 | 2017-09-26 | — | — | CN | disclosed |