Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27841831 | 0.84 | POLB (0.68) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL28182822 | 0.82 | ALDH1A1 (0.63) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL21972581 | 0.80 | ALDH1A1 (0.64) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL20537061 | 0.80 | KDM4E (0.72) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL28640545 | 0.79 | ALDH1A1 (0.75) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL19277764 | 0.79 | GAA (0.75) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL3808723 | 0.78 | GAA (1.00) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL11900441 | 0.76 | ALDH1A1 (0.70) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL1275812 | 0.75 | KMT2A (0.72) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL5105924 | 0.75 | POLB (0.68) | ALDH1A1GAAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107245044-B | 2- (naphthylamino thioformyl) hydrazine benzyl formate compound, synthetic method and application | 华南师范大学 | 2019-11-15 | — | — | CN | disclosed |
| CN-107245044-A | 2‑（Naphthylamino thioformyl）Hydrazine benzyl formate compound, synthetic method and application | 华南师范大学 | 2017-10-13 | — | — | CN | disclosed |