Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23848 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL5709311 | 0.92 | — | — | |
| SCHEMBL454017 | 0.87 | — | — | |
| Adipic Acid SCHEMBL28268122 | 0.87 | LMNA (0.58) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL9504707 | 0.87 | LMNA (0.58) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL9352237 | 0.85 | TSHR (0.60) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL3761638 | 0.85 | TSHR (0.60) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL504189 | 0.85 | TSHR (0.60) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL2210214 | 0.85 | TSHR (0.60) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL609292 | 0.85 | TSHR (0.60) | LMNASLC22A6TSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829644-B | A kind of preparation method of (S) tertiary butyl dimethyl Si base glutaric acid list benzyl ester monoamides | 浙江新东港药业股份有限公司 | 2017-11-14 | — | — | CN | disclosed |