Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 3/20 | 0.32 |
| ▸ | FLT3 | P36888 | 3/20 | 0.32 |
| ▸ | FYN | P06241 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28183202 | 0.87 | MAPK1 (0.41) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL28183316 | 0.86 | KDM4E (0.33) | SMN1; SMN2SRCFLT3FYNKDM4E | |
| SCHEMBL28184049 | 0.81 | DDB1 (0.38) | SMN1; SMN2LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL28852897 | 0.76 | HSP90AA1 (0.40) | SMN1; SMN2LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL28184098 | 0.72 | MAPK1 (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28183172 | 0.66 | DDB1 (0.38) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL18207631 | 0.65 | TLR7 (0.52) | HTT | |
| SCHEMBL28184066 | 0.64 | TLR7 (0.32) | KDM4E | |
| SCHEMBL28184056 | 0.63 | POLB (0.36) | LMNAMAPTHTTALDH1A1SRC | |
| SCHEMBL18207388 | 0.60 | CA1 (0.50) | SRCFLT3FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107580596-A | For treating and preventing the new sulphur imido acyl group purinone compound and derivative of virus infection | 豪夫迈·罗氏有限公司 | 2018-01-12 | — | — | CN | disclosed |