Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28183316 | 0.90 | KDM4E (0.33) | HSP90AA1TLR7KDM4ESMN1; SMN2 | |
| SCHEMBL28184098 | 0.88 | MAPK1 (0.39) | HSP90AA1ALDH1A1THRBTLR7NPC1 | |
| SCHEMBL28183172 | 0.84 | DDB1 (0.38) | ALDH1A1TLR7NPC1LMNARAB9A | |
| SCHEMBL28183208 | 0.83 | ABCB1 (0.38) | ALDH1A1TLR7KDM4ENPC1LMNA | |
| SCHEMBL28183202 | 0.76 | MAPK1 (0.41) | HSP90AA1ALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL28184056 | 0.76 | POLB (0.36) | ALDH1A1TLR7KDM4ELMNARAB9A | |
| SCHEMBL28183273 | 0.76 | SMN1; SMN2 (0.33) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL20343752 | 0.75 | ADORA2A (0.39) | TLR7LMNA | |
| SCHEMBL28184079 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TLR7 | |
| SCHEMBL14944658 | 0.75 | TLR7 (0.36) | ALDH1A1THRBTLR7KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107580596-A | For treating and preventing the new sulphur imido acyl group purinone compound and derivative of virus infection | 豪夫迈·罗氏有限公司 | 2018-01-12 | — | — | CN | disclosed |