Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.58 |
| ▸ | F3 | P13726 | 1/20 | 0.58 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.58 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.58 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.58 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.58 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL28731875 | 1.00 | F7 (0.58) | F7F3SARM1SIRT2SIRT6 | |
| Ribose (Furanose) SCHEMBL18185139 | 0.91 | F7 (0.59) | F7F3SARM1SIRT2SIRT6 | |
| Ribose (Furanose) SCHEMBL14321532 | 0.91 | F7 (0.59) | F7F3SARM1SIRT2SIRT6 | |
| Ribose (Furanose) SCHEMBL338518 | 0.91 | F7 (0.59) | F7F3SARM1SIRT2SIRT6 | |
| Ribose (Furanose) SCHEMBL23111913 | 0.90 | F7 (0.58) | F7F3SARM1SIRT2SIRT6 | |
| Ribose (Furanose) SCHEMBL17315074 | 0.88 | F7 (0.56) | F7F3SARM1SIRT2SIRT6 | |
| Niacin SCHEMBL28253394 | 0.88 | ALDH1A1 (0.57) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL29859929 | 0.87 | F7 (0.55) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL20398298 | 0.87 | F7 (0.55) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL21074249 | 0.87 | F7 (0.55) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849083-A | Nicotinamide nucleoside and pterostilbene compositions and methods for treating skin disorders | 益力舒健康公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107428791-A | The crystal form of nicotinamide riboside | 格雷斯公司 | 2017-12-01 | — | — | CN | disclosed |