Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL28136690 | 0.92 | F7 (0.51) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL17315028 | 0.91 | F7 (0.50) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL28137384 | 0.91 | F7 (0.50) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL21571784 | 0.91 | F7 (0.50) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL502654 | 0.90 | F7 (0.49) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL30498617 | 0.89 | F7 (0.48) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL28184048 | 0.89 | F7 (0.48) | F7F3SARM1SIRT2SIRT6 | |
| Ribose (Furanose) SCHEMBL14321532 | 0.88 | F7 (0.59) | F7F3SARM1SIRT2SIRT6 | |
| Ribose (Furanose) SCHEMBL338518 | 0.88 | F7 (0.59) | F7F3SARM1SIRT2SIRT6 | |
| Ribose (Furanose) SCHEMBL18185139 | 0.88 | F7 (0.59) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11926644-B2 | Syntheses, activities, and methods of use of dihydronicotinamide riboside derivatives | CORNELL UNIVERSITY (US) | 2024-03-12 | — | — | US | disclosed |
| US-20210355152-A1 | SYNTHESES, ACTIVITIES, AND METHODS OF USE OF DIHYDRONICOTINAMIDE RIBOSIDE DERIVATIVES | CORNELL UNIVERSITY (US) | 2021-11-18 | — | — | US | disclosed |
| US-10392414-B2 | Syntheses, activities, and methods of use of dihydronicotinamide riboside derivatives | CORNELL UNIVERSITY (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180208619-A1 | SYNTHESES, ACTIVITIES, AND METHODS OF USE OF DIHYDRONICOTINAMIDE RIBOSIDE DERIVATIVES | CORNELL UNIVERSITY (US) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208619-A1 | SYNTHESES, ACTIVITIES, AND METHODS OF USE OF DIHYDRONICOTINAMIDE RIBOSIDE DERIVATIVES | NQO1, NME4, NQO2 | F7 4379/4885F3 1211/4885SARM1 8/4885 |
| US-20210355152-A1 | SYNTHESES, ACTIVITIES, AND METHODS OF USE OF DIHYDRONICOTINAMIDE RIBOSIDE DERIVATIVES | NQO1, NME4, NQO2 | F7 4379/4885F3 1211/4885SARM1 8/4885 |
| US-10392414-B2 | Syntheses, activities, and methods of use of dihydronicotinamide riboside derivatives | NQO1, NME4, NQO2 | F7 4379/4885F3 1211/4885SARM1 8/4885 |
| US-11926644-B2 | Syntheses, activities, and methods of use of dihydronicotinamide riboside derivatives | NQO1, NME4, NQO2 | F7 4379/4885F3 1211/4885SARM1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.