Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2019967 | 0.82 | ADRA1A (0.46) | ADRA1AKMT2APROKR1HCRTR2DRD4 | |
| SCHEMBL25044963 | 0.82 | ADRA1A (0.40) | ADRA1AKMT2APROKR1RIPK1HCRTR2 | |
| SCHEMBL251063 | 0.80 | ADRA1A (0.45) | ADRA1AKMT2APROKR1RIPK1HCRTR2 | |
| SCHEMBL27840667 | 0.78 | ADRA1A (0.37) | ADRA1AKMT2APROKR1HCRTR2DRD4 | |
| SCHEMBL29580963 | 0.78 | ADRA1A (0.49) | ADRA1AKMT2APROKR1RIPK1HCRTR2 | |
| SCHEMBL3167985 | 0.78 | ADRA1A (0.49) | ADRA1AKMT2APROKR1RIPK1HCRTR2 | |
| SCHEMBL18040831 | 0.77 | MEN1 (0.43) | KMT2ACNR2PDE10A | |
| Phenol SCHEMBL11490133 | 0.73 | ESR2 (0.42) | ADRA1AKMT2APROKR1RIPK1HCRTR2 | |
| SCHEMBL16455042 | 0.72 | DRD2 (0.55) | — | |
| SCHEMBL20139888 | 0.72 | HTR2C (0.49) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107344940-A | BTK inhibitor and application thereof | 广东东阳光药业有限公司 | 2017-11-14 | — | — | CN | disclosed |