SCHEMBL28185686

SCHEMBL28185686

C=C(C(=O)OCCCCCCCCCCCCOC(=O)C(=C)C(C)(C)C)C(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
ALDH1A1 P00352 2/20 0.40
CYP3A4 P08684 1/20 0.40
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NAAA Q02083 1/20 0.38
RAD52 P43351 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
EPHX1 P07099 1/20 0.35
THRB P10828 1/20 0.35
ACHE P22303 6/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28791986 0.93 TSHR (0.44) TSHRALDH1A1CYP3A4POLBAPEX1
SCHEMBL28328479 0.92 TSHR (0.65) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL28126298 0.92 TSHR (0.65) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL28122100 0.92 TSHR (0.65) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL787671 0.90 TSHR (0.61) TSHRALDH1A1CYP3A4NAAARAD52
SCHEMBL9746066 0.88 TSHR (0.53) TSHRALDH1A1TDP1NAAARAD52
SCHEMBL28122699 0.88 TSHR (0.42) TSHRALDH1A1CYP3A4POLBAPEX1
SCHEMBL9297852 0.86 TSHR (0.39) TSHRPOLBAPEX1HTTTDP1
Acrylic Acid SCHEMBL20261905 0.83 TSHR (0.54) TSHRALDH1A1CYP3A4NAAARAD52
SCHEMBL27438786 0.83 TSHR (0.42) TSHRALDH1A1TDP1THRBHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103748122-B The polymer of functionalization 艾勒旺斯可再生科学公司 2017-11-10 CN disclosed