Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746066 | 0.88 | TSHR (0.53) | TSHRTHRBHCAR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL787671 | 0.86 | TSHR (0.61) | TSHRHCAR2ALDH1A1LMNAHPGD | |
| SCHEMBL28791986 | 0.84 | TSHR (0.44) | TSHRTHRBALDH1A1TDP1HPGD | |
| SCHEMBL8744223 | 0.84 | ALDH1A1 (0.47) | TSHRTHRBALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28122100 | 0.84 | TSHR (0.65) | TSHRHCAR2ALDH1A1LMNA | |
| SCHEMBL28328479 | 0.84 | TSHR (0.65) | TSHRHCAR2ALDH1A1LMNA | |
| SCHEMBL28126298 | 0.84 | TSHR (0.65) | TSHRHCAR2ALDH1A1LMNA | |
| SCHEMBL27558586 | 0.83 | TSHR (0.42) | TSHRTHRBHCAR2ALDH1A1GAA | |
| SCHEMBL28185686 | 0.83 | TSHR (0.52) | TSHRTHRBHCAR2ALDH1A1TDP1 | |
| SCHEMBL1896769 | 0.82 | ALDH1A1 (0.48) | TSHRTHRBALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043802-A | POSITIVE SOLID BLOCK TONER | DU PONT (US) | 1990-07-11 | — | — | CN | disclosed |