Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185686 | 0.93 | TSHR (0.52) | TSHRTHRBALDH1A1HPGDPOLB | |
| SCHEMBL9746066 | 0.90 | TSHR (0.53) | TSHRTHRBALDH1A1HPGDTDP1 | |
| SCHEMBL9297852 | 0.88 | TSHR (0.39) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL787671 | 0.88 | TSHR (0.61) | TSHRALDH1A1HPGDCYP3A4ATM | |
| SCHEMBL28122100 | 0.86 | TSHR (0.65) | TSHRALDH1A1NAAA | |
| SCHEMBL28328479 | 0.86 | TSHR (0.65) | TSHRALDH1A1NAAA | |
| SCHEMBL28126298 | 0.86 | TSHR (0.65) | TSHRALDH1A1NAAA | |
| SCHEMBL27438786 | 0.84 | TSHR (0.42) | TSHRTHRBALDH1A1HPGDTDP1 | |
| SCHEMBL22545152 | 0.83 | THRB (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL534164 | 0.83 | THRB (0.34) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102010490-B | Method for preparing degradable multiblock polymer | UNIV ZHEJIANG | 2014-04-16 | — | — | CN | disclosed |
| CN-102010490-A | Method for preparing degradable multiblock polymer | UNIV ZHEJIANG | 2011-04-13 | — | — | CN | disclosed |