Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16088995 | 0.87 | HPGDS (0.51) | HPGDSCYP2A6KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL2819462 | 0.82 | ALDH1A1 (0.47) | HPGDSKDM4ESMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL12279413 | 0.80 | HPGDS (0.71) | HPGDSCYP2A6KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL2820252 | 0.77 | HPGDS (0.54) | HPGDSCYP2A6KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL16807424 | 0.76 | HPGDS (0.50) | HPGDSCYP2A6KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL16088982 | 0.76 | HPGDS (0.41) | HPGDSCYP2A6KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL19034303 | 0.76 | HPGDS (0.41) | HPGDSCYP2A6KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL10022413 | 0.76 | CYP2A6 (0.56) | CYP2A6KDM4ESMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL17803411 | 0.75 | HPGDS (0.68) | HPGDSCYP2A6KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL23367916 | 0.74 | KDM4E (0.46) | KDM4ESMN1; SMN2CYP3A4CYP2C9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590942-B1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2016-05-04 | — | — | EP | disclosed |
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | DONG WHA PHARMACEUTICAL IND. CO., LTD. | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | CMA1, IL5, HRH4 | HPGDS 595/4885CYP2A6 505/4885KDM4E 1350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.