SCHEMBL28186146

SCHEMBL28186146

[O]C1C(=O)c2ccccc2OC1c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.51
KDR P35968 1/20 0.51
CYP19A1 P11511 7/20 0.50
MAOB P27338 4/20 0.50
ADORA3 P0DMS8 2/20 0.50
KDM4E B2RXH2 1/20 0.50
AR P10275 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CYP3A4 P08684 2/20 0.44
MAPT P10636 2/20 0.44
MAPK1 P28482 2/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
HTR2B P41595 1/20 0.44
ALDH1A1 P00352 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
DNMT3B Q9UBC3 1/20 0.40
STK17B O94768 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16376660 0.81 ESR1 (0.55) RETKDRCYP19A1MAOBADORA3
SCHEMBL3439134 0.80 RET (0.77) RETKDRCYP19A1MAOBADORA3
SCHEMBL10516436 0.80 RET (0.50) RETKDRCYP19A1MAOBADORA3
SCHEMBL29367518 0.80 RET (0.77) RETKDRCYP19A1MAOBADORA3
SCHEMBL3362960 0.80 RET (0.77) RETKDRCYP19A1MAOBADORA3
SCHEMBL8394789 0.80 RET (0.50) RETKDRCYP19A1MAOBADORA3
SCHEMBL24115843 0.80 RET (0.77) RETKDRCYP19A1MAOBADORA3
SCHEMBL11043870 0.80 ESR1 (0.56) RETKDRCYP19A1MAOBADORA3
SCHEMBL5579742 0.80 ESR1 (0.56) RETKDRCYP19A1MAOBADORA3
SCHEMBL29843330 0.80 RET (0.77) RETKDRCYP19A1MAOBADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107475416-A For screening the primer of reference gene and its application under wax-apple low temperature stress 福建省农业科学院果树研究所 2017-12-15 CN disclosed
CN-107385104-A For screening primer pair and its application of wax-apple Fruit Development Process reference gene 福建省农业科学院果树研究所 2017-11-24 CN disclosed