Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043870 | 1.00 | ESR1 (0.56) | ESR1RETKDRCYP19A1MAOB | |
| SCHEMBL7522409 | 0.88 | ESR1 (0.56) | ESR1RETKDRCYP19A1MAOB | |
| SCHEMBL5579748 | 0.88 | ESR1 (0.56) | ESR1RETKDRCYP19A1MAOB | |
| SCHEMBL24227321 | 0.81 | ESR1 (0.68) | ESR1CYP19A1MAOBAR | |
| SCHEMBL4360680 | 0.81 | ESR1 (0.86) | ESR1CYP19A1MAOBADORA3KDM4E | |
| SCHEMBL28186146 | 0.80 | RET (0.51) | RETKDRCYP19A1MAOBADORA3 | |
| SCHEMBL16376660 | 0.80 | ESR1 (0.55) | ESR1RETKDRCYP19A1MAOB | |
| SCHEMBL92288 | 0.79 | ESR1 (0.45) | ESR1RETKDRCYP19A1MAOB | |
| SCHEMBL9434848 | 0.79 | ESR1 (0.45) | ESR1RETKDRCYP19A1MAOB | |
| SCHEMBL8702376 | 0.79 | ESR1 (0.45) | ESR1RETKDRCYP19A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8852757-B2 | Organic electroluminescence element, lighting device and display device | KONICA MINOLTA HOLDINGS, INC. (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20110006670-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20100152285-A1 | Flavononol Renin Inhibitor Compounds and Methods of Use Thereof | HERBALSCIENCE GROUP LLC (US) | 2010-06-17 | — | — | US | disclosed |
| US-20100045171-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20090092624-A1 | Antiinfective Flavononol Compounds and Methods of Use Thereof | HERBALSCIENCE GROUP, LLC | 2009-04-09 | — | — | US | disclosed |
| US-20070299032-A1 | Method and Composition for Thickening Hair | SHISEIDO COMPANY, LTD. (JP) | 2007-12-27 | — | — | US | disclosed |
| US-20070184098-A1 | Esters of flavonoids with w-substituted c6-c22 fatty acids | COGNIS FRANCE S.A. (FR) | 2007-08-09 | — | — | US | disclosed |
| CN-1878530-A | Method and composition for hair thickening | SHISEIDO CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |
| EP-1683509-A1 | METHOD AND COMPOSITION FOR HAIR THICKENING | SHISEIDO COMPANY, LTD. (JP) | 2006-07-26 | — | — | EP | disclosed |
| EP-0025599-B1 | BENZOPYRAN COMPOUNDS, USEFUL AS CHEMOTHERAPEUTIC AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-12-19 | — | — | EP | disclosed |
| US-4452991-A | OR BENZO(B)INDENO (2,1-E) PYRANS OR BENZO(C)XANTHENES | BATCHELOR JOHN F (GB) | 1984-06-05 | — | — | US | disclosed |
| EP-0025599-A1 | Benzopyran compounds, useful as chemotherapeutic agents | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152285-A1 | Flavononol Renin Inhibitor Compounds and Methods of Use Thereof | REN, ACE, AGT | ESR1 2912/4885RET 2710/4885KDR 1306/4885 |
| US-20090092624-A1 | Antiinfective Flavononol Compounds and Methods of Use Thereof | MPO, VIP, FABP2 | ESR1 2919/4885RET 4882/4885KDR 4873/4885 |
| US-20110006670-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME | AOC2, AOC3, CDYL | ESR1 67/4885RET 2773/4885KDR 4039/4885 |
| US-20070184098-A1 | Esters of flavonoids with w-substituted c6-c22 fatty acids | FADS1, FADS2, FASN | ESR1 515/4885RET 4822/4885KDR 2369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.