Propene

Propene

SCHEMBL28186167

C=CC.C=Cc1c(C(=O)O)ccc(C(=O)O)c1C=C

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.49
SLC22A8 Q8TCC7 1/20 0.49
CYP1A2 P05177 1/20 0.44
ALDH1A1 P00352 7/20 0.39
ALOX15 P16050 2/20 0.39
MCL1 Q07820 1/20 0.38
SELL P14151 1/20 0.37
SELP P16109 1/20 0.37
GABRP O00591 2/20 0.36
GABRD O14764 2/20 0.36
GABRA1 P14867 2/20 0.36
GABRB1 P18505 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRA5 P31644 2/20 0.36
GABRA3 P34903 2/20 0.36
GABRA2 P47869 2/20 0.36
GABRB2 P47870 2/20 0.36
GABRA4 P48169 2/20 0.36
GABRE P78334 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL332990 0.93 CYP1A2 (0.50) SLC22A6SLC22A8CYP1A2ALDH1A1ALOX15
SCHEMBL7869868 0.79 SLC22A6 (0.51) SLC22A6SLC22A8CYP1A2ALDH1A1MCL1
SCHEMBL27494534 0.79 ALDH1A1 (0.52) SLC22A6SLC22A8ALDH1A1ALOX15TSHR
SCHEMBL31084599 0.78 SLC22A8 (0.66) SLC22A6SLC22A8CYP1A2ALDH1A1MCL1
SCHEMBL27479146 0.78 SLC22A6 (0.47) SLC22A6SLC22A8CYP1A2ALDH1A1MCL1
SCHEMBL28841150 0.77 SLC22A6 (0.46) SLC22A6SLC22A8CYP1A2ALDH1A1MCL1
Phthalic Acid SCHEMBL7192838 0.76 ALDH1A1 (0.70) ALDH1A1ALOX15TSHRCA12CA1
Phthalic Acid SCHEMBL9722583 0.76 ALDH1A1 (0.70) ALDH1A1ALOX15TSHRCA12CA1
SCHEMBL9439534 0.75 SLC22A6 (0.41) SLC22A6SLC22A8CYP1A2ALDH1A1ALOX15
SCHEMBL8058926 0.75 TSHR (0.47) SLC22A6SLC22A8CYP1A2ALDH1A1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107286596-A Polymer-coated silver nano-grain sulfonated polyester composite powder of styrene-based and preparation method thereof 施乐公司 2017-10-24 CN disclosed