Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EIF4E | P06730 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28186234 | 0.82 | FBP1 (0.41) | MEN1KMT2AMAPTIDO1TDO2 | |
| SCHEMBL28185578 | 0.81 | IDO1 (0.40) | MEN1KMT2AMAPTLMNAIDO1 | |
| SCHEMBL7918730 | 0.81 | ABCC1 (0.49) | MEN1KMT2AMAPTHPGDIDO1 | |
| SCHEMBL28185546 | 0.79 | SCN2A (0.44) | MEN1KMT2AMAPTHPGDEIF4E | |
| SCHEMBL28185537 | 0.79 | NPC1 (0.53) | MEN1KMT2AMAPTLMNAHPGD | |
| SCHEMBL2331528 | 0.73 | ALDH1A1 (0.65) | EGFREIF4ENPC1RAB9ATP53 | |
| SCHEMBL28853237 | 0.73 | ALDH1A1 (0.40) | MEN1KMT2AMAPTLMNAIDO1 | |
| SCHEMBL28185543 | 0.72 | TSHR (0.42) | MAPTLMNANPSR1IDO1SMN1; SMN2 | |
| SCHEMBL10519102 | 0.71 | SMN1; SMN2 (0.43) | MEN1KMT2AMAPTNPSR1IDO1 | |
| SCHEMBL17283633 | 0.69 | TDP1 (0.45) | MEN1KMT2AMAPTSMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382892-A | A kind of preparation technology of the nitro isoxazole compound of 3 aryl 4 | 贵州大学 | 2017-11-24 | — | — | CN | disclosed |