Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28186251

C1CC1.C1CCOC1.CC(C)=O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
SMN1; SMN2 Q16637 3/20 0.42
LMNA P02545 1/20 0.40
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35
KMT2A Q03164 1/20 0.35
PKM P14618 1/20 0.33
GAA P10253 1/20 0.32
TSHR P16473 2/20 0.31
TTR P02766 1/20 0.31
GLA P06280 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
PIK3CD O00329 1/20 0.30
KDM4E B2RXH2 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL10806048 1.00 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2LMNAMEN1TP53
Acetone SCHEMBL8877074 1.00 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2LMNAMEN1TP53
Acetone SCHEMBL2230779 1.00 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2LMNAMEN1TP53
Tetrahydrofuran SCHEMBL165529 0.97
Dioxane SCHEMBL10806051 0.93 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2LMNAMEN1TP53
Tetrahydrofuran SCHEMBL6927933 0.93 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2LMNAMEN1TP53
Tetrahydrofuran SCHEMBL11690381 0.93 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2LMNAMEN1TP53
Acetic Acid SCHEMBL29037898 0.90 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2LMNAMEN1TP53
Tetrahydrofuran SCHEMBL18917647 0.90 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2LMNAMEN1TP53
Acetic Acid SCHEMBL2354574 0.90 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2LMNAMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107353944-B A kind of high density cage modle heat absorbing type liquid carbon hydrogen fuel and preparation method thereof 湖北航天化学技术研究所 2019-03-12 CN claimed
CN-107353944-A A kind of high density cage modle heat absorbing type liquid carbon hydrogen fuel and preparation method thereof 湖北航天化学技术研究所 2017-11-17 CN claimed