Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1909166 | 0.88 | GRM2 (0.53) | GRM2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2821953 | 0.87 | LMNA (0.54) | GRM2ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL28595790 | 0.87 | ESR1 (0.55) | GRM2ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL3092869 | 0.86 | HSD17B10 (0.51) | GRM2ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL553801 | 0.86 | GRM2 (0.53) | GRM2ALDH1A1LMNAKLKB1KDM4E | |
| SCHEMBL554548 | 0.86 | GRM2 (0.51) | GRM2ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL16246754 | 0.86 | KLKB1 (0.57) | GRM2ALDH1A1LMNAKLKB1HSD17B10 | |
| SCHEMBL30739239 | 0.85 | GRM2 (0.50) | GRM2ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL3093449 | 0.85 | GRM2 (0.63) | GRM2ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL30739426 | 0.85 | GRM2 (0.50) | GRM2ALDH1A1LMNAKLKB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | PPARA, PPARD, PPARG | GRM2 849/4885ALDH1A1 461/4885LMNA 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.