SCHEMBL3092869

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1909166	0.92	GRM2 (0.53)	HSD17B10GRM2KLKB1KDM4EALDH1A1
	SCHEMBL2821953	0.90	LMNA (0.54)	HSD17B10GRM2KLKB1ALDH1A1SMN1; SMN2
	SCHEMBL28595790	0.90	ESR1 (0.55)	HSD17B10GRM2KLKB1KDM4EALDH1A1
	SCHEMBL554548	0.89	GRM2 (0.51)	HSD17B10GRM2KLKB1KDM4EALDH1A1
	SCHEMBL553801	0.89	GRM2 (0.53)	HSD17B10GRM2KLKB1KDM4EALDH1A1
	SCHEMBL16246754	0.89	KLKB1 (0.57)	HSD17B10GRM2KLKB1ALDH1A1LMNA
	SCHEMBL3093449	0.88	GRM2 (0.63)	GRM2KLKB1ALDH1A1SMN1; SMN2MAPT
	SCHEMBL30739426	0.88	GRM2 (0.50)	HSD17B10GRM2KLKB1KDM4EALDH1A1
	SCHEMBL30739239	0.88	GRM2 (0.50)	HSD17B10GRM2KLKB1KDM4EALDH1A1
	SCHEMBL553854	0.88	HSD17B10 (0.60)	HSD17B10GRM2KLKB1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.