SCHEMBL28186341

SCHEMBL28186341

O=CNc1n[nH]cc1C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 2/20 0.32
HCAR2 Q8TDS4 1/20 0.32
NOTUM Q6P988 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28433433 0.73 HCAR3 (0.37) KDM5AHCAR2NOTUM
SCHEMBL27961033 0.72 TSHR (0.32)
SCHEMBL28014585 0.71 DHODH (0.54)
SCHEMBL27789484 0.71
SCHEMBL27829971 0.71
SCHEMBL3319032 0.71 HCAR2 (0.38) HCAR2NOTUM
SCHEMBL553835 0.69 GABRP (0.44) KDM5AHCAR2NOTUM
SCHEMBL27472244 0.69
SCHEMBL28426901 0.69 KDM5B (0.57) HCAR2
SCHEMBL28398432 0.68 KCNN4 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428732-A Substituted 2-thioimidazolyl carboxamides as pest control agents 拜耳作物科学股份公司 2017-12-01 CN disclosed