Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11741377 | 0.79 | MAPT (0.58) | PYCR1MAPTCA12CA9CA1 | |
| SCHEMBL11078522 | 0.77 | MAPT (0.53) | PYCR1MAPTCA12CA9CA1 | |
| SCHEMBL31592520 | 0.77 | CA12 (0.53) | PYCR1MAPTCA12CA9CA1 | |
| SCHEMBL17076659 | 0.77 | CA12 (0.58) | MAPTCA12CA9CA1CA2 | |
| SCHEMBL4225554 | 0.77 | CA12 (0.53) | PYCR1MAPTCA12CA9CA1 | |
| SCHEMBL566097 | 0.77 | MAPT (0.53) | PYCR1MAPTCA12CA9CA1 | |
| SCHEMBL13192623 | 0.77 | CA2 (0.46) | MAPTCA9CA2MEN1KMT2A | |
| SCHEMBL1036594 | 0.76 | KCNH3 (0.58) | MAPTCA12CA9CA1CA2 | |
| SCHEMBL20540341 | 0.76 | MAPT (0.52) | PYCR1MAPTCA12CA9CA1 | |
| Hydrochloric Acid SCHEMBL31362621 | 0.74 | KCNH3 (0.61) | MAPTCA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510507-A | Palladium-catalyzed indoline quinoline derivative synthesized by intramolecular dearomatization of indole and preparation method thereof | 河北工业大学 | 2024-02-06 | — | — | CN | disclosed |
| CN-114805093-B | Preparation method of diarylamines | 暨南大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-114805093-A | Preparation method of diarylamine compound | 暨南大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-109336829-B | Aryl formamide compound containing 1,2, 3-triazole structure and application thereof | 沈阳药科大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-109336829-A | Aryl methanamide compounds of the triazole structure containing 1,2,3- and application thereof | 沈阳药科大学 | 2019-02-15 | — | — | CN | disclosed |
| CN-107459491-A | Benzamide compound containing 1,2,3 triazole structures and application thereof | 沈阳药科大学 | 2017-12-12 | — | — | CN | disclosed |