Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1754735 | 0.82 | POLB (0.57) | ATMNPSR1JAK2JAK1TYK2 | |
| SCHEMBL8480564 | 0.79 | JAK2 (0.51) | ATMNPSR1JAK2JAK1TYK2 | |
| SCHEMBL4040084 | 0.79 | HPGD (0.46) | ATMNPSR1JAK2JAK1TYK2 | |
| SCHEMBL1754686 | 0.75 | GSK3B (0.49) | ALDH1A1ALOX15TP53RPS6KA3DYRK1A | |
| SCHEMBL22643908 | 0.75 | JAK2 (0.44) | ATMNPSR1JAK2JAK1TYK2 | |
| SCHEMBL4045467 | 0.75 | CYP1A2 (0.43) | ATMNPSR1JAK2JAK1TYK2 | |
| SCHEMBL705177 | 0.74 | MAPT (0.56) | NPSR1ALOX15TP53RETCYP1A2 | |
| SCHEMBL8479885 | 0.74 | ALDH1A1 (0.43) | ATMNPSR1JAK2JAK1TYK2 | |
| SCHEMBL27598057 | 0.74 | PIN1 (0.56) | ALDH1A1BTKCYP1A2PRMT5 | |
| SCHEMBL15579658 | 0.72 | TP53 (0.56) | ATMNPSR1ALOX15TP53RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107446840-A | One plant of 2 pyridazinone degradation bacteria of 6 hydroxyl of phenyl 3 and its application | 江苏南资环保股份有限公司 | 2017-12-08 | — | — | CN | claimed |