Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12993787 | 0.86 | KMT2A (0.50) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL12994024 | 0.84 | KMT2A (0.49) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL28186785 | 0.83 | KMT2A (0.61) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL10103705 | 0.78 | KMT2A (0.76) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL28888813 | 0.77 | KMT2A (0.59) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL26357170 | 0.76 | CYP1A2 (0.37) | MAPTKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL12994021 | 0.75 | KMT2A (0.40) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL7154389 | 0.75 | KMT2A (0.51) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL24343952 | 0.75 | PIK3CB (0.43) | MAPTKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL29534406 | 0.75 | PIK3CB (0.43) | MAPTKDM4EALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107445991-A | A kind of Phosphine ligands of indoles skeleton and its preparation method and application | 香港理工大学深圳研究院 | 2017-12-08 | — | — | CN | disclosed |