Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.47 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28186785 | 0.84 | KMT2A (0.61) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL30444195 | 0.78 | KMT2A (0.69) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL3690560 | 0.78 | KMT2A (0.69) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL16638211 | 0.77 | HTR6 (0.51) | KMT2AMEN1KDM4EALDH1A1RECQL | |
| SCHEMBL14614655 | 0.77 | MAPT (0.57) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL28275724 | 0.76 | KMT2A (0.65) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL28187484 | 0.75 | KMT2A (0.54) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL22245740 | 0.75 | KDM4E (0.39) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL22245795 | 0.73 | SCN9A (0.42) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL10103705 | 0.73 | KMT2A (0.76) | KMT2AMEN1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108094-A2 | SULFONAMIDE-SUBSTITUTED CHALCONE DERIVATIVES AND THEIR USE TO TREAT DISEASES | ATHEROGENICS, INC. (US) | 2004-12-16 | — | — | WO | disclosed |