Fluoride

Fluoride

SCHEMBL28188685

F.N=C=Nc1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.52
ALDH1A1 P00352 2/20 0.43
HTR3E A5X5Y0 2/20 0.35
HTR3B O95264 2/20 0.35
HTR3A P46098 2/20 0.35
HTR3D Q70Z44 2/20 0.35
HTR3C Q8WXA8 2/20 0.35
SLC22A2 O15244 1/20 0.35
SLC22A1 O15245 1/20 0.35
SLC22A3 O75751 1/20 0.35
PLAU P00749 1/20 0.35
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
MAPT P10636 3/20 0.33
NOS1 P29475 3/20 0.33
NOS3 P29474 2/20 0.33
RAB9A P51151 2/20 0.33
PKM P14618 1/20 0.33
HTT P42858 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132994 0.97
Ethylene SCHEMBL15090386 0.92 MIF (0.50) MIFALDH1A1HTR3EHTR3BHTR3A
Ethylamine SCHEMBL27850605 0.84 MIF (0.43) MIFALDH1A1HTR3EHTR3BHTR3A
SCHEMBL27989093 0.82 ALDH1A1 (0.43) MIFALDH1A1CYP1A2TDP1CYP1A1
SCHEMBL21644817 0.78 NOS1 (0.37) MIFALDH1A1NOS1
Carbimide SCHEMBL28053096 0.78 MIF (0.52) MIFALDH1A1HTR3EHTR3BHTR3A
SCHEMBL17067443 0.76 MIF (0.50) MIFALDH1A1HTR3EHTR3BHTR3A
SCHEMBL28893803 0.74 CYP3A4 (0.48) MIFALDH1A1HTR3EHTR3BHTR3A
Phenylisothiocyanate SCHEMBL3484791 0.74 MIF (0.85) MIFALDH1A1MEN1KMT2AMAPT
SCHEMBL28583699 0.74 CYP3A4 (0.48) MIFALDH1A1HTR3EHTR3BHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107473991-A By the synthetic method of the isourea of catalysis of rare-earth compound 苏州大学 2017-12-15 CN disclosed