Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 5/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCND2 | P30279 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823560 | 0.89 | KMT2A (0.35) | KDM4EMAPTKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2823122 | 0.84 | ALDH1A1 (0.38) | ATMKDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL2821626 | 0.84 | SMN1; SMN2 (0.34) | KDM4EMAPTKMT2AEIF4A1L3MBTL1 | |
| SCHEMBL2820005 | 0.81 | ALDH1A1 (0.34) | KDM4EMAPTKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2819625 | 0.81 | GAA (0.37) | KDM4EMAPTKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2820343 | 0.80 | ELANE (0.34) | ATMELANEESR1KDM4EMAPT | |
| SCHEMBL2821628 | 0.79 | SRC (0.34) | CCNT1CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL2821878 | 0.78 | ELANE (0.33) | ATMELANEKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL22966207 | 0.78 | KMT2A (0.36) | KDM4EMAPTKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2823578 | 0.77 | ALDH1A1 (0.33) | KDM4EMAPTKMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386914-B1 | HALOGENATED QUINOLINE DERIVATIVES AND ECTOPARASITE CONTROLLERS | MEIJI SEIKA KAISHA (JP) | 2010-10-27 | — | — | EP | disclosed |