Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820547 | 0.91 | ALDH1A1 (0.32) | ALDH1A1LMNAHPGDSMN1; SMN2TDP1 | |
| SCHEMBL2823122 | 0.89 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDKDM4EL3MBTL1 | |
| SCHEMBL2823560 | 0.86 | KMT2A (0.35) | ALDH1A1LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL2823361 | 0.84 | GAA (0.35) | ALDH1A1LMNAHPGDKDM4EL3MBTL1 | |
| SCHEMBL2823578 | 0.83 | ALDH1A1 (0.33) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL2819625 | 0.83 | GAA (0.37) | ALDH1A1LMNAHPGDKDM4EL3MBTL1 | |
| SCHEMBL2818871 | 0.81 | ATM (0.35) | ALDH1A1KDM4EL3MBTL1KMT2AMAPT | |
| SCHEMBL2819552 | 0.79 | KDM4E (0.32) | ALDH1A1TDP1KDM4EL3MBTL1MEN1 | |
| SCHEMBL2821626 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL28456406 | 0.79 | GAA (0.37) | ALDH1A1LMNAHPGDKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386914-B1 | HALOGENATED QUINOLINE DERIVATIVES AND ECTOPARASITE CONTROLLERS | MEIJI SEIKA KAISHA (JP) | 2010-10-27 | — | — | EP | disclosed |