SCHEMBL28189178

SCHEMBL28189178

Cc1cccc(C(O)=S)c1-c1ccc(C(C)(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39
THRB P10828 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
FABP4 P15090 1/20 0.37
DHODH Q02127 1/20 0.37
MYC P01106 1/20 0.37
RXRB P28702 1/20 0.36
TSHR P16473 1/20 0.35
KIF11 P52732 2/20 0.35
PPARG P37231 1/20 0.35
NR1H4 Q96RI1 1/20 0.35
SMO Q99835 1/20 0.34
LMNA P02545 1/20 0.34
TYR P14679 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
ASIC1 P78348 1/20 0.34
TRPV1 Q8NER1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28470502 0.87 MYC (0.42) TP53THRBSMN1; SMN2FABP4DHODH
SCHEMBL4785732 0.84 MYC (0.51) TP53THRBSMN1; SMN2FABP4DHODH
SCHEMBL28301230 0.83 TP53 (0.39) TP53THRBSMN1; SMN2FABP4KIF11
SCHEMBL5608923 0.80 TSHR (0.48) TP53SMN1; SMN2DHODHTSHRKIF11
SCHEMBL28189433 0.76 MAPT (0.54) TP53THRBSMN1; SMN2FABP4MYC
SCHEMBL19582848 0.75 RORB (0.43) SMN1; SMN2KIF11LMNATYRNPC1
SCHEMBL14046205 0.74 SMN1; SMN2 (0.45) TP53THRBSMN1; SMN2KIF11SMO
SCHEMBL4741015 0.73 ALDH1A1 (0.49) DHODHTSHRPPARGNPC1RAB9A
SCHEMBL135115 0.70 SMO (0.50) FABP4DHODHMYCRXRBSMO
SCHEMBL29979402 0.70 SMO (0.50) FABP4DHODHMYCRXRBSMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107365266-B Novel sulfonium compound and its manufacturing method, anti-corrosion agent composition and pattern forming method 信越化学工业株式会社 2019-06-11 CN disclosed
CN-107365266-A New sulfonium compound and its manufacture method, anti-corrosion agent composition and pattern formation method 信越化学工业株式会社 2017-11-21 CN disclosed