Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.46 |
| ▸ | TEK | Q02763 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244019 | 0.90 | L3MBTL1 (0.61) | L3MBTL1CREBBPHDAC1HSD17B10ADORA2A | |
| SCHEMBL25365603 | 0.86 | L3MBTL1 (0.76) | L3MBTL1EPHB4KDRCREBBPKCNH2 | |
| SCHEMBL3103391 | 0.81 | NOTUM (0.54) | L3MBTL1KCNH2HSD17B10 | |
| SCHEMBL2821950 | 0.80 | HSD17B10 (0.43) | L3MBTL1EPHB4KDRTEKKCNH2 | |
| SCHEMBL3085851 | 0.80 | LMNA (0.61) | L3MBTL1CREBBPKCNH2HSD17B10SCD5 | |
| SCHEMBL2819206 | 0.78 | HSP90AB1 (0.49) | L3MBTL1HSP90AB1HDAC1KLKB1 | |
| SCHEMBL3085028 | 0.76 | GAA (0.55) | L3MBTL1HSD17B10 | |
| SCHEMBL18235821 | 0.76 | KMT2A (0.66) | L3MBTL1KCNH2HSD17B10 | |
| SCHEMBL2822506 | 0.76 | HSD17B10 (0.40) | L3MBTL1KCNH2HSD17B10KLKB1 | |
| SCHEMBL2052581 | 0.76 | L3MBTL1 (0.52) | L3MBTL1HSP90AB1ADORA2AADORA1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | PPARA, PPARD, PPARG | L3MBTL1 4855/4885EPHB4 1067/4885KDR 828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.