Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28189724 | 0.94 | ACLY (0.36) | ACLYCCR2 | |
| SCHEMBL16235686 | 0.79 | ACLY (0.38) | ACLY | |
| SCHEMBL16254675 | 0.75 | — | — | |
| SCHEMBL16235915 | 0.74 | — | — | |
| SCHEMBL16657417 | 0.72 | NUDT1 (0.41) | ACLYPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28189725 | 0.72 | BACE1 (0.47) | — | |
| SCHEMBL16235887 | 0.68 | NUDT1 (0.40) | — | |
| SCHEMBL15416636 | 0.66 | NUDT1 (0.40) | — | |
| SCHEMBL16236021 | 0.65 | PPARG (0.39) | — | |
| SCHEMBL16236263 | 0.65 | NUDT1 (0.39) | ACLYCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105392787-B | For treating and preventing the azepine oxindole of respiratory syncytial virus infection | 豪夫迈·罗氏有限公司 | 2017-11-24 | — | — | CN | disclosed |