Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782788 | 0.86 | ALDH1A1 (0.36) | HTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6033729 | 0.74 | NOS2 (0.44) | HTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL25208543 | 0.73 | — | — | |
| SCHEMBL12832925 | 0.73 | PDPK1 (0.35) | HTTALDH1A1 | |
| SCHEMBL16155044 | 0.72 | TAAR1 (0.39) | HTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16155048 | 0.71 | ADORA2A (0.35) | HTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15271545 | 0.70 | ADORA2A (0.42) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL678617 | 0.69 | EGFR (0.36) | HTTALDH1A1LMNA | |
| SCHEMBL12776668 | 0.69 | ALDH1A1 (0.39) | HTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3818212 | 0.69 | KDM4E (0.36) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989049-B | Vif inhibitor and application thereof in preparation of anti-HIV (human immunodeficiency Virus) medicament | 四川大学华西医院 | 2023-06-27 | — | — | CN | disclosed |
| CN-114989049-A | Vif inhibitor and application thereof in preparation of anti-HIV (human immunodeficiency virus) medicines | 四川大学华西医院 | 2022-09-02 | — | — | CN | disclosed |
| CN-107011347-B | A kind of synthetic method of chloro- 7H- pyrrolo- [2,3-d] pyrimidine of 4- | 华东师范大学 | 2019-01-18 | — | — | CN | disclosed |
| CN-107011347-A | A kind of synthetic method of 4 chlorine 7H pyrrolo-es [2,3 d] pyrimidines | 华东师范大学 | 2017-08-04 | — | — | CN | disclosed |