Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 5/20 | 0.37 |
| ▸ | PGR | P06401 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28190799 | 0.84 | CA12 (0.47) | APPF2RL3PGRKDM4EALDH1A1 | |
| SCHEMBL12937258 | 0.82 | APP (0.41) | APPF2RL3PGRKDM4EALDH1A1 | |
| SCHEMBL34470866 | 0.79 | F2RL3 (0.40) | APPF2RL3PGRKDM4EALDH1A1 | |
| SCHEMBL34471429 | 0.79 | CYP19A1 (0.41) | APPF2RL3PGRKDM4EALDH1A1 | |
| SCHEMBL30443494 | 0.78 | MAOB (0.40) | APPKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL12173327 | 0.78 | ALDH1A1 (0.43) | APPF2RL3KDM4EALDH1A1HPGD | |
| SCHEMBL676612 | 0.75 | KDM4E (0.45) | KDM4EALDH1A1HPGDMAPTCYP2A6 | |
| SCHEMBL18585563 | 0.74 | CYP2A6 (0.43) | PGRKDM4EMAPTCYP2A6MEN1 | |
| SCHEMBL12321280 | 0.73 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDMAPTEPHX2 | |
| SCHEMBL15888125 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1HPGDMAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209444-B | It can be used as the benzo-fused heterocycle derivative of GPR120 activator | 詹森药业有限公司 | 2017-12-29 | — | — | CN | disclosed |