Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiazolidine SCHEMBL3313313 | 0.80 | BCHE (0.38) | KDM4EHPGDALDH1A1MAPTFLT3 | |
| SCHEMBL24045384 | 0.79 | KDM4E (0.42) | KDM4EHPGDCYP2A6FLT3LOXL2 | |
| SCHEMBL28750544 | 0.78 | MAPT (0.45) | KDM4EHPGDALDH1A1MAPTCYP2A6 | |
| SCHEMBL800706 | 0.78 | KDM4E (0.44) | KDM4EHPGDALDH1A1CYP2A6FLT3 | |
| SCHEMBL16595609 | 0.77 | FLT3 (0.49) | KDM4EHPGDALDH1A1FLT3RAB9A | |
| SCHEMBL28190799 | 0.75 | CA12 (0.47) | KDM4EHPGDALDH1A1MAPTCYP2A6 | |
| SCHEMBL8036000 | 0.75 | KDM4E (0.46) | KDM4EHPGDALDH1A1MAPTCYP2A6 | |
| SCHEMBL23692162 | 0.75 | MAOB (0.43) | KDM4EHPGDALDH1A1CYP2A6FLT3 | |
| SCHEMBL5776749 | 0.75 | FLT3 (0.46) | KDM4EHPGDALDH1A1MAPTCYP2A6 | |
| SCHEMBL28190093 | 0.75 | APP (0.39) | KDM4EHPGDALDH1A1MAPTCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417316-A | Trifluoromethyl benzofuran derivative and preparation method thereof | 陕西科技大学 | 2024-01-19 | — | — | CN | claimed |
| CN-110590722-B | Synthesis method of 2-trifluoromethyl benzofuran derivative | 温州大学 | 2022-11-04 | — | — | CN | claimed |
| CN-112210132-B | Oil-resistant corrosion-resistant heel mark material and preparation method thereof | 浙江中瑞橡胶高分子材料股份有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-113122061-A | Quantum dot ink and preparation method of quantum dot film | TCL集团股份有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-112210132-A | Oil-resistant corrosion-resistant heel mark material and preparation method thereof | 浙江中瑞橡胶高分子材料股份有限公司 | 2021-01-12 | — | — | CN | claimed |
| CN-110590722-A | Synthesis method of 2-trifluoromethyl benzofuran derivative | 温州大学 | 2019-12-20 | — | — | CN | claimed |
| US-4939140-A | ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1990-07-03 | — | — | US | claimed |
| CN-117417316-B | Trifluoromethyl benzofuran derivative and preparation method thereof | 陕西科技大学 | 2026-03-27 | — | — | CN | disclosed |
| CN-117417316-B | Trifluoromethyl benzofuran derivative and preparation method thereof | 陕西科技大学 | 2026-03-27 | — | — | CN | disclosed |
| CN-116874452-B | Synthesis method for synthesizing 3-methylbenzofuran structural compound by taking calcium carbide as alkynyl source | 宁夏大学 | 2025-04-01 | — | — | CN | disclosed |
| CN-117460288-A | Organic electroluminescent device, display panel and display device | 京东方科技集团股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117417316-A | Trifluoromethyl benzofuran derivative and preparation method thereof | 陕西科技大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-117417316-A | Trifluoromethyl benzofuran derivative and preparation method thereof | 陕西科技大学 | 2024-01-19 | — | — | CN | disclosed |
| US-7192971-B2 | 4-Heteroaryl-tetrahydroquinolines and their use as inhibitors of the cholesterin-ester transfer protein | BAYER AKTIENGESELLSCHAFT (DE) | 2007-03-20 | — | — | US | disclosed |
| US-7192971-B2 | 4-Heteroaryl-tetrahydroquinolines and their use as inhibitors of the cholesterin-ester transfer protein | BAYER AKTIENGESELLSCHAFT (DE) | 2007-03-20 | — | — | US | disclosed |
| US-20070054839-A1 | Method of inhibiting remnant lipoprotein production | JAPAN TOBACCO INC. (JP) | 2007-03-08 | — | — | US | disclosed |
| US-20070054839-A1 | Method of inhibiting remnant lipoprotein production | JAPAN TOBACCO INC. (JP) | 2007-03-08 | — | — | US | disclosed |
| WO-2005117869-A1 | COMBINATIONS COMPRISING (S)-AMLODIPINE AND A CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITOR, AND METHODS FOR REDUCING HYPERTENSION | SEPRACOR INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| WO-2004004777-A1 | USE OF CETP INHIBITORS AND ANTIHYPERTENSIVE AGENTS AS WELL AS OPTIONALLY HMG COA REDUCTASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2004-01-15 | — | — | WO | disclosed |
| WO-2004004778-A1 | USE OF CETP INHIBITORS AND OPTIONALLY HMG COA REDUCTABLE INHIBITORS AND/OR ANTIHYPERTENSIVE AGENTS | PFIZER PRODUCTS INC. (US) | 2004-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054839-A1 | Method of inhibiting remnant lipoprotein production | CETP, PCSK9, LIPA | KDM4E 2545/4885HPGD 1620/4885ALDH1A1 3285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.